Genes affected by de novo mutations in schizophrenia, filtered for genes occurring in the initial Epi4K cohort and annotated for all other studies that have used trio exome sequencing on a large scale in neurodevelopmental disorders. In green, de novo mutations in controls or unaffected sibs are shown. SCN2A clearly stands out as a gene that is found in a broad range of phenotypes.
Child Neurology Fellow and epilepsy genetics researcher at the Children’s Hospital of Philadelphia (CHOP), USA and Department of Neuropediatrics, Kiel, Germany
