Study design of the publication by Michaelson and collaborators. The authors sequencing 10 monozygotic twins with autism and their parents to identify de novo mutations. They found that de novo mutations are correlated with specific genomic features and that some of the known autism genes are hypermutable.
Child Neurology Fellow and epilepsy genetics researcher at the Children’s Hospital of Philadelphia (CHOP), USA and Department of Neuropediatrics, Kiel, Germany
