Local heritability exceeds single-SNP based heritability at known GWAS loci. The phenotypes from the WTCCC included Bipolar Disorder (BD), Coronary Artery Disease (CAD), Crohn’s Disease (CD), Hypertension (HT), Rheumatoid Arthritis (RA), Type 1 Diabetes (T1D), Type 2 Diabetes (T2D), Multiple Sclerosis (MS), Ulcerative Colitis (UC). Image modified under a creative commons license from

Ingo Helbig

Child Neurology Fellow and epilepsy genetics researcher at the Children’s Hospital of Philadelphia (CHOP), USA and Department of Neuropediatrics, Kiel, Germany

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