Roland’s density plot of >12,000 genes in the human genome annotated for their pathogenicity score and RVIS. We have highlighted a few genes known to be related to human seizure disorders and two genes (MUC7, FAM198A) that we frequently see in exomes, as they are highly variable.

Roland Krause

Roland is a bioinformatician at the Luxembourg Centre for Systems Biomedicine. He received his undergraduate degree in biotechnological engineering and a PhD in biochemistry from the University of Heidelberg. His postdoc was in computational biology at the MPI for Molecular Genetics, Berlin, shared with the computer science and math department of the Free University Berlin.

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