Auditory. The next gene in our weekly review is LGI1. We chose LGI1 for mainly two reasons. First, it is not a gene for epileptic encephalopathies, but for familial focal epilepsies and we are currently working up a large family with an LGI1 mutation. While the conditions of the mTOR pathways were discussed quite frequently, LGI1 was a little left behind. Secondly, there were various updates on LGI1 that didn’t really warrant a full post. Therefore, we have collected this in a summary post. Continue reading →