The ACMG recommendations try to find a middleground between the two extreme opionions relating the data return on incidental genomic findings. On the one hand, genetic liberitarians suggest that incidental findings should be returned even for variants with unknown significance as patients are entitled to know about these findings. On the other hand, genetic empiricists suggest that little is known about the penetrance of pathogenic mutations on the population level and that a liberal return of incidental findings places a high burden on individuals, turning them into “patients in waiting”.