The role of CLCN2 mutations in IGE remains questionable. This paper by Saint-Martin et al. describes two novel CLCN2 variants in Idiopathic Generalised Epilepsy and show that the variation has functional effects on channel function.
Ingo
This 2009 blog post has been transferred to the EuroEPINOMICS blog from www.epilepsygenetics.net.
Please quote this blog (APA format) as
Helbig, I. The return of CLCN2. Retrieved [enter date], from http://www.euroepinomics.wordpress.com
Child Neurology Fellow and epilepsy genetics researcher at the Children’s Hospital of Philadelphia (CHOP), USA and Department of Neuropediatrics, Kiel, Germany
